Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 196
  • Home
  • Print this page
  • Email this page
CASE-BASED REVIEW
Year : 2017  |  Volume : 3  |  Issue : 1  |  Page : 124-131

Part 1: Café-au-lait macule – Presentation and genesis


1 Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA
2 Department of Family Medicine, St. Luke's University Health Network, Bethlehem, Pennsylvania, USA
3 Department of Internal Medicine, St. Luke's University Health Network, Bethlehem, Pennsylvania, USA
4 Department of Pathology, St. Luke's University Health Network, Bethlehem, Pennsylvania, USA

Correspondence Address:
Sudip Nanda
Department of Internal Medicine, St. Luke's University Hospital Network, 801 Ostrum Street, Bethlehem, Pennsylvania 18015
USA
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2455-5568.209836

Rights and Permissions

Café-au-lait macules (CALMs) are clinically significant presentations of isolated hyperpigmentation whose mechanism evades discovery. While not always of pathogenic origin, CALMs manifest in a number of diseases, implying a diversely regulated and interconnected developmental pathway. In this paper, we highlight a patient presenting with an undiagnosed, systemic condition and multiple CALMs as a backdrop for approaching the pathogenesis of hyperpigmentation. We underscore the key players in melanogenesis with the goal of better elucidating the mechanisms involved in pathogenic CALMs. The following core competencies are addressed in this article: Patient care, Medical knowledge.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3783    
    Printed94    
    Emailed0    
    PDF Downloaded15    
    Comments [Add]    

Recommend this journal